Vitamin D Receptor Human Recombinant ( VDR Human )

Data sheet

Formulation

VDR protein is supplied in 50mM Tris, 150mM NaCl and 10% Glycerol, pH 7.5.

Purity

Greater than 70.0% as determined by SDS-PAGE.

Description

Vitamin D Receptor Human Recombinant produced in E.Coli is a full length protein consisting of 427 amino acids having a molecular weight of 48.3kDa and fused with 5.5kDa amino-terminal His-Flag tag.VDR is purified by proprietary chromatographic techniques

Protein Background

Vitamin D receptors (VDRs) belong to the NR1I family, which also includes pregnane X (PXR) and constitutive androstane (CAR) receptors which form heterodimers with members of the retinoid X receptor family. VDR is expressed in the intestine, thyroid and k

Expression host

Escherichia Coli.

Synonyms

Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1.

Reagent Appearance

Sterile filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.

Amino acid sequence

MSYYHHHHHHDYDIPTTDYKDDDDKDYKDDDDKENLYFQGEFMEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSD