XRCC2 Human

Data sheet

Formulation

The XRCC2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

Purity

Greater than 80% as determined by SDS-PAGE.

Description

XRCC2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 303 amino acids (1-280) and having a molecular mass of 34.3 kDa. XRCC2 is fused to a 23 amino acid His-tag at N-terminus.

Protein Background

XRCC2 belongs to the RecA/Rad51-related protein family which takes part in homologous recombination to repair DNA damage and preserve chromosome stability. XRCC2 gene participates in the mending of DNA double-strand disruptions by homologous recombination

Expression host

Escherichia Coli.

Synonyms

X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 2, X-Ray Repair Cross-Complementing Protein 2, RAD51-like, DNA Repair Protein XRCC2.

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMCSAFHR AESGTELLAR LEGRSSLKEI EPNLFADEDS PVHGDILEFH GPEGTGKTEM LYHLTARCIL PKSEGGLEVE VLFIDTDYHF DMLRLVTILE HRLSQSSEEI IKYCLGRFFL VYCSSSTHLL LTLYSLESMF CSHPSLCLLI LDSLSAFYWI DRVNGGESVN LQESTLRKCS QCLEKLVNDY RLVLFATTQT IMQKASSSSE EP