UMOD Feline

Data sheet

Formulation

The UMOD protein was lyophilized from 0.4um filtered solution at a concentration of 0.5mg/ml containing deionized water.

Solubility

Add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Purity

Greater than 95% as determined by SDS-PAGE.

Description

Feline Uromodulin is a 95kDa glycoprotein which is produced in the thick ascending limb of Henles loop and early distal convoluted tubules of the nephron.

Protein Background

Uromodulin is the most abundant protein in normal urine. Its secretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uro

Expression host

Feline Urine.

Synonyms

Tamm-Horsfall urinary glycoprotein, THP, FJHN, HNFJ, THGP, MCKD2, ADMCKD2, UMOD, Uromodulin.

Reagent Appearance

Filtered White lyophilized (freeze-dried) powder.

Stability

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.