| Formulation |
THAP7 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea. |
| Purity |
Greater than 85.0% as determined by SDS-PAGE. |
| Description |
THAP7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 332 amino acids (1-309 a.a) and having a molecular mass of 36.8kDa. THAP7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background |
THAP Domain Containing, Apoptosis Associated Protein 7 (THAP7) holds one THAP-type zinc finger. THAP7 is a chromatin-associated, histone tail-binding protein which represses transcription by recruiting HDAC3 and nuclear hormone receptor corepressors. |
| Expression host |
Escherichia Coli. |
| Synonyms |
THAP domain containing 7, THAP7. |
| Reagent Appearance |
Sterile Filtered colorless solution. |
| Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MGSMPRHCSA AGCCTRDTRE TRNRGISFHR LPKKDNPRRG LWLANCQRLD PSGQGLWDPA SEYIYFCSKH FEEDCFELVG ISGYHRLKEG AVPTIFESFS KLRRTTKTKG HSYPPGPAEV SRLRRCRKRC SEGRGPTTPF SPPPPADVTC FPVEEASAPA TLPASPAGRL EPGLSSPFSD LLGPLGAQAD EAGCSAQPSP ERQPSPLEPR PVSPSAYMLR LPPPAGAYIQ NEHSYQVGSA LLWKRRAEAA LDALDKAQRQ LQACKRREQR LRLRLTKLQQ ERAREKRAQA DARQTLKEHV QDFAMQLSSS MA. |
