SNRPA Human

Data sheet

Formulation

SNRPA is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol.

Purity

Greater than 90% as determined by SDS-PAGE.

Description

SNRPA Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 32,102 Dalton. SNRPA is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.

Protein Background

SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is essential for splicing. The SNRPA protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dim

Expression host

Sf9 insect cells.

Synonyms

U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A, SNRPA, Mud1.

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.