SIX1 Human

Data sheet

Formulation

The SIX1 solution contains 20mM Tris-HCl buffer (pH 8.0), 2M Urea and 10% glycerol.

Purity

Greater than 85% as determined by SDS-PAGE.

Description

SIX1 Human Recombinant produced in E. coli is a single polypeptide chain containing 308 amino acids (1-284) and having a molecular mass of 34.7 kDa.SIX1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques

Protein Background

Homeobox protein SIX1 (SIX1) belongs to the SIX gene family. SIX1 is characterized by a divergent DNA-binding homeodomain and an upstream SIX domain, which is involved both in determining DNA-binding specificity and in mediating protein-protein interactio

Expression host

E.coli.

Synonyms

SIX Homeobox 1, Sine Oculis Homeobox Homolog 1, Sine Oculis Homeobox Homolog 1 (Drosophila), Homeobox Protein SIX1, Deafness Autosomal Dominant 23, DFNA23, TIP39, BOS3.

Reagent Appearance

Sterile Filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSHMSMLPS FGFTQEQVAC VCEVLQQGGN LERLGRFLWS LPACDHLHKN ESVLKAKAVV AFHRGNFREL YKILESHQFS PHNHPKLQQL WLKAHYVEAE KLRGRPLGAV GKYRVRRKFP LPRTIWDGEE TSYCFKEKSR GVLREWYAHN PYPSPREKRE LAEATGLTTT QVSNWFKNRR QRDRAAEAKE RENTENNNSS SNKQNQLSPL EG