| Clone |
P1E8AT. |
| Protein Background |
SBDS is part of an extremely preserved protein family which exists from archaea to vertebrates and plants. SBDS protein functions in RNA metabolism and has a role in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Shwachman-Diamond syndrome is a rare autosomal recessive disorder produced by mutations in the SBDS gene. |
| Synonyms |
SDS, SWDS, Shwachman-Bodian-Diamond syndrome, Ribosome Maturation protein SBDS. |
| Type |
Mouse Anti Human Monoclonal. |
| Immunogen |
Anti-human SBDS mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SBDS amino acids 1-250 purified from E. coli. |
| Ig Subclass |
Mouse IgG2b heavy chain and kappa light chain. |
| Purification Method |
SBDS antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Protein formulation |
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. |
| Storage Procedures |
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
| Stability / Shelf Life |
12 months at -20°C. 1 month at 4°C. |
