PIM2 Human

Data sheet

Formulation

PIM2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol.

Purity

Greater than 85.0% as determined by SDS-PAGE.

Description

PIM2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 334 amino acids (1-311 a.a) and having a molecular mass of 36.6kDa. PIM2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chrom

Protein Background

PIM2 is a serine/threonine protein kinase which is a part of the CAMK family. PIM2 is expressed in various tissues mainly in spleen, thymus, testis and small intestine. PIM2 is implicated in tumor phenotypes and participates in the formation and preservat

Expression host

Escherichia Coli.

Synonyms

Pim-2 oncogene, Serine/threonine-protein kinase pim-2, Pim-2h, PIM2.

Reagent Appearance

Sterile Filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMLTKPLQ GPPAPPGTPT PPPGGKDREA FEAEYRLGPL LGKGGFGTVF AGHRLTDRLQ VAIKVIPRNR VLGWSPLSDS VTCPLEVALL WKVGAGGGHP GVIRLLDWFE TQEGFMLVLE RPLPAQDLFD YITEKGPLGE GPSRCFFGQV VAAIQHCHSR GVVHRDIKDE NILIDLRRGC AKLIDFGSGA LLHDEPYTDF DGTRVYSPPE WI