PI3 Human

Data sheet

Formulation

PI3 protein solution (0.25mg/ml) containing 20mM Tris-HCl (pH8.0), 0.15M NaCl,10% glycerol and 1mM DTT.

Purity

Greater than 80.0% as determined by SDS-PAGE.

Description

PI3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 118 amino acids (23-117 a.a) and having a molecular mass of 12kDa.PI3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatog

Protein Background

Peptidase Inhibitor 3 also known as PI3 is an elastase-specific protease inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and therefore belongs to the WFDC domain family. The majority WFDC gene members are localized to chromosome 20

Expression host

Escherichia Coli.

Synonyms

Peptidase Inhibitor 3, Skin-Derived, Skin-Derived Antileukoproteinase, Protease Inhibitor 3, Skin-Derived (SKALP), WAP Four-Disulfide Core Domain Protein 14, Elastase-Specific Inhibitor, Protease Inhibitor WAP3, Trappin-2, WFDC14, SKALP, PI-3, WAP3, ESI,

Reagent Appearance

Sterile Filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSAVTGVPV KGQDTVKGRV PFNGQDPVKG QVSVKGQDKV KAQEPVKGPV STKPGSCPII LIRCAMLNPP NRCLKDTDCP GIKKCCEGSC GMACFVPQ