| Formulation |
The LRP2BP solution (0.5mg/1ml) contains Phosphate buffered saline (pH7.4), 20% glycerol and 1mM DTT. |
| Purity |
Greater than 95.0% as determined by SDS-PAGE. |
| Inactivation |
Protein quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.91 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of MIP-3b as a Reference Standard. |
| Description |
LRP2BP Human Recombinant produced in E. coli is a single polypeptide chain containing 370 amino acids (1-347) and having a molecular mass of 42.2kDa.LRP2BP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background |
LRP2 Binding Protein (LRP2BP) is a protein coding gene which plays a role as an adapter that controls LRP2 function. LRP2BP is noticed in a vesicular staining pattern close to the plasma membrane and through the cytoplasm. |
| Expression host |
Escherichia Coli. |
| Synonyms |
LRP2-binding protein, KIAA1325, LRP2BP, LRP2 Binding Protein, Megalin-binding protein, MegBP. |
| Reagent Appearance |
Sterile Filtered clear solution. |
| Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MGSMKLTSEK LPKNPFYASV SQYAAKNQKF FQWKKEKTDY THANLVDKAL QLLKERILKG DTLAYFLRGQ LYFEEGWYEE ALEQFEEIKE KDHQATYQLG VMYYDGLGTT LDAEKGVDYM KKILDSPCPK ARHLKFAAAY NLGRAYYEGK GVKRSNEEAE RLWLIAADNG NPKASVKAQS MLGLYYSTKE PKELEKAFYW HSEACGNGNL ESQGALGLMY LYGQGIRQDT EAALQCLREA AERGNVYAQG NLVEYYYKMK FFTKCVAFSK RIADYDEVHD IPMIAQVTDC LPEFIGRGMA MASFYHARCL QLGLGITRDE TTAKHYYSKA CRLNPALADE LHSLLIRQRI. |
