| Formulation |
The ISOC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Purity |
Greater than 90.0% as determined by SDS-PAGE. |
| Description |
ISOC2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 170 amino acids (59-205) and having a molecular mass of 18kDa.ISOC2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background |
Isochorismatase Domain Containing 2, also known as ISOC2, is a part of the isochorismatase family. SOC2 is localized in mitochondrion, cytoplasm, and nucleus. ISOC2 which interacts with CDKN2A is localizes to the nucleus in the attendance of CDKN2A. |
| Expression host |
Escherichia Coli. |
| Synonyms |
Isochorismatase domain-containing protein 2, mitochondrial, ISOC2, Isochorismatase Domain Containing 2. |
| Reagent Appearance |
Sterile Filtered colorless solution. |
| Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MGSEQYPQGL GPTVPELGTE GLRPLAKTCF SMVPALQQEL DSRPQLRSVL LCGIEAQACI LNTTLDLLDR GLQVHVVVDA CSSRSQVDRL VALARMRQSG AFLSTSEGLI LQLVGDAVHP QFKEIQKLIK EPAPDSGLLG LFQGQNSLLH. |
