HOMER2 Human

Data sheet

Formulation

The HOMER2 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 1mM DTT and 10% glycerol.

Purity

Greater than 85% as determined by SDS-PAGE.

Description

HOMER2 Human Recombinant produced in E. coli is a single polypeptide chain containing 368 amino acids (1-343) and having a molecular mass of 42.1kDa.HOMER2 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniq

Protein Background

HOMER2 belongs to the homer family of dendritic proteins which are immediate early gene products who bind to group 1 metabotropic glutamate receptors (mGluRs), proteins associated to triggering intracellular calcium release. Additionally, HOMER2 conect mG

Expression host

E.coli.

Synonyms

Homer homolog 2 (Drosophila), homer neuronal immediate early gene 2, homer homolog 3, HOMER-2 (2A/2B), Vesl-2, ACPD, Cupidin, CPD.

Reagent Appearance

Sterile Filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSHMMGEQP IFTTRAHVFQ IDPNTKKNWM PASKQAVTVS YFYDVTRNSY RIISVDGAKV IINSTITPNM TFTKTSQKFG QWADSRANTV FGLGFSSEQQ LTKFAEKFQE VKEAAKIAKD KTQEKIETSS NHSQASSVNG TDDEKASHAG PANTHLKSEN DKLKIALTQS AANVKKWEIE LQTLRESNAR LTTALQESAA SVEQWKRQFS IC