GM CSF Human, CHO

Data sheet

Formulation

The GM CSF Human filtered solution (0.27mg/ml) contains 20mM TRIS HCl buffer pH 7.2.

Purity

Greater than 95% as determined by SDS-PAGE.

Description

GM CSF Human Recombinant produced in CHO cells is a 14.6kDa globular protein consisting of 127 amino acids, having two intramolecular disulfide bonds and two N-linked glycosylation sites.

Protein Background

Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was first characterized as a growth factor that supports the in-vitro colony formation of granulocytes-macrophages progenitor cells (1, 2). It is a pleiotropic cytokine and a member of a family of

Expression host

Chinese Hamster Ovary cells.

Synonyms

CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim, MGC131935, MGC138897.

Reagent Appearance

Sterile filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

APARSPSPST QPWEHVNAIQ EARRLLNLSR DTAAEMNETV EVISEMFDLQ EPTCLQTRLE LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFESFKENL KDFLLVIPFD CWEPVQE

Biological Activity

ED50

Product Description

Immunoreactive with sera HBV-infected individuals.