| Formulation |
The FTSJ2 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 30% glycerol. |
| Purity |
Greater than 95% as determined by SDS-PAGE. |
| Description |
FTSJ2 Human Recombinant produced in E. coli is a single polypeptide chain containing 219 amino acids (51-246) and having a molecular mass of 24.1 kDa.FTSJ2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background |
FtsJ RNA Methyltransferase Homolog 2 (FTSJ2) belongs to the S-adenosylmethionine-binding protein family. FTSJ2 is a nucleolar protein and which is involved in cell cycle control and DNA repair and the processing and modification of rRNA. FTSJ2 is extensively expressed, with the highest expression in the muscle, placenta, and heart. |
| Expression host |
E.coli. |
| Synonyms |
FtsJ RNA methyltransferase homolog 2 (E. coli), putative ribosomal RNA methyltransferase 2, MRM2 RNA methyltransferase homolog, rRNA (uridine-2'-O-)-methyltransferase, cell division protein FtsJ, Protein ftsJ homolog 2, MRM2, FJH1, EC 2.1.1.-. |
| Reagent Appearance |
Sterile Filtered colorless solution. |
| Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MGSSYRCRSA FKLLEVNERH QILRPGLRVL DCGAAPGAWS QVAVQKVNAA GTDPSSPVGF VLGVDLLHIF PLEGATFLCP ADVTDPRTSQ RILEVLPGRR ADVILSDMAP NATGFRDLDH DRLISLCLTL LSVTPDILQP GGTFLCKTWA GSQSRRLQRR LTEEFQNVRI IKPEASRKES SEVYFLATQY HGRKGTVKQ |
