FOLR1 Human

Data sheet

Formulation

FOLR1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Description

FOLR1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 233 amino acids (25-234 a.a) and having a molecular mass of 27kDa. FOLR1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chro

Protein Background

Folate Receptor 1, also known as FOLR1, is a part of the folate receptor family whose members bind folic acid. FOLR1 binds to folate and reduced folic acid derivatives and facilitates transfer of 5-methyltetrahydrofolate and folate analogs into the cells.

Expression host

Escherichia Coli.

Synonyms

Folate Receptor 1 (Adult), Ovarian Tumor-Associated Antigen MOv18, Adult Folate-Binding Protein, Folate Receptor Adult , KB Cells FBP, FR-Alpha, FOLR, FBP, Folate Binding Protein, Folate Receptor Alpha, Folate Receptor 1.

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSRIAWART ELLNVCMNAK HHKEKPGPED KLHEQCRPWR KNACCSTNTS QEAHKDVSYL YRFNWNHCGE MAPACKRHFI QDTCLYECSP NLGPWIQQVD QSWRKERVLN VPLCKEDCEQ WWEDCRTSYT CKSNWHKGWN WTSGFNKCAV GAACQPFHFY FPTPTVLCNE IWTHSYKVSN YSRGSGRCIQ MWFDPAQGNP NEEVARFYAA AM