FKBP5 Human

Data sheet

Formulation

FKBP5 was filtered (0.4um) and lyophilized in 20mM Tris buffer and 50mM NaCl, pH 7.5.

Solubility

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Filter sterilize your culture media/working solutions containing this non-sterile FKBP5 before using

Purity

Greater than 90.0% as determined by SDS-PAGE.

Description

FKBP5 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (Met1-Val457) containing 467 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 52.5kDa.

Protein Background

FK506 Binding Protein 5 (FKBP5) belongs to the immunophilin protein family, which has a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP5 is a cis-trans prolyl isomerase, which binds to the immunosuppre

Expression host

Escherichia Coli.

Synonyms

FK506 Binding Protein 5, 54 KDa Progesterone Receptor-Associated Immunophilin, 51 KDa FK506-Binding Protein, Androgen-Regulated Protein 6, HSP90-Binding Immunophilin, FK506-Binding Protein 5, PPIase FKBP5, 51 KDa FKBP, FF1 Antigen, EC 5.2.1.8, Rotamase, F

Reagent Appearance

Filtered White lyophilized (freeze-dried) powder.

Stability

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Amino acid sequence

MKHHHHHHASMTTDEGAKNN EESPTATVAE QGEDITSKKD RGVLKIVKRV GNGEETPMIG DKVYVHYKGK LSNGKKFDSS HDRNEPFVFS LGKGQVIKAW DIGVATMKKG EICHLLCKPE YAYGSAGSLP KIPSNATLFF EIELLDFKGE DLFEDGGIIR RTKRKGEGYS NPNEGATVEI HLEGRCGGRM FDCRDVAFTV GEGEDHDIPI GIDKALEKMQ REEQCILYLG PRY