Formulation |
ETS2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea. |
Purity |
Greater than 85.0% as determined by SDS-PAGE. |
Description |
ETS2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 489 amino acids (1-469 a.a) and having a molecular mass of 55.1kDa. ETS2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Protein Background |
V-Ets Avian Erythroblastosis Virus E26 Oncogene 2 (ETS2) is a transcription factor that regulates genes involved in development and apoptosis. ETS2 is also a protooncogene which takes part in regulation of telomerase. ETS2 proteins pseudogene is located on the X chromosome. |
Expression host |
Escherichia Coli. |
Synonyms |
Protein C-ets-2, ETS2, V-Ets Avian Erythroblastosis Virus E26 Oncogene 2, V-ets erythroblastosis virus E26 oncogene homolog 2, ETS2IT1. |
Reagent Appearance |
Sterile Filtered colorless solution. |
Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MNDFGIKNMD QVAPVANSYR GTLKRQPAFD TFDGSLFAVF PSLNEEQTLQ EVPTGLDSIS HDSANCELPL LTPCSKAVMS QALKATFSGF KKEQRRLGIP KNPWLWSEQQ VCQWLLWATN EFSLVNVNLQ RFGMNGQMLC NLGKERFLEL APDFVGDILW EHLEQMIKEN QEKTEDQYEE NSHLTSVPHW INSNTLGFGT EQAPYGMQTQ NYPKGGLLDS MCPASTPSVL SSEQEFQMFP KSRLSSVSVT YCSVSQDFPG SNLNLLTNNS GTPKDHDSPE NGADSFESSD SLLQSWNSQS SLLDVQRVPS FESFEDDCSQ SLCLNKPTMS FKDYIQERSD PVEQGKPVIP AAVLAGFTGS GPIQLWQFLL ELLSDKSCQS FISWTGDGWE FKLADPDEVA RRWGKRKNKP KMNYEKLSRG LRYYYDKNII HKTSGKRYVY RFVCDLQNLL GFTPEELHAI LGVQPDTED. |