Clone |
NYRhEPO. |
Applications |
Direct ELISA, Western Blot, Immuneprecipitation. |
Inactivation |
Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm using the absorbency value of 0.8511 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of Fibroblast Growth Factor-b as a Reference Standard. |
Protein Background |
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. |
Synonyms |
EPO-a, EPO-alpha, Epoetin, EP, MGC138142. |
Type |
Mouse Anti Human Monoclonal. |
Immunogen |
r.Human erythropoietin. |
Ig Subclass |
Mouse IgG1. |
Purification Method |
Ion exchange. |
Storage Procedures |
In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |