CTSL Human

Data sheet

Formulation

CTSL protein solution (1mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol.

Purity

Greater than 90% as determined by SDS-PAGE.

Description

CTSL Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 339 amino acids (18-333 a.a) and having a molecular mass of 38.3kDa.CTSL is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chrom

Protein Background

Cathepsin-L also known as CTSL is a member of the peptidase C1 family. CTSL, is a dimer composed of disulfide-linked heavy and light chains, both formed from a single protein precursor. Furthermore, CTSL is a lysosomal cysteine proteinase which takes a ma

Expression host

Escherichia Coli.

Synonyms

Cathepsin L, CTSL1, Cathepsin L1, Major Excreted Protein, MEP, EC 3.4.22.15, CATL, EC 3.4.22.

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSTLTFDHS LEAQWTKWKA MHNRLYGMNE EGWRRAVWEK NMKMIELHNQ EYREGKHSFT MAMNAFGDMT SEEFRQVMNG FQNRKPRKGK VFQEPLFYEA PRSVDWREKG YVTPVKNQGQ CGSCWAFSAT GALEGQMFRK TGRLISLSEQ NLVDCSGPQG NEGCNGGLMD YAFQYVQDNG GLDSEESYPY EATEESCKYN PKYSVANDTG FV