| Formulation |
The CST5 solution (0.5mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol. |
| Purity |
Greater than 90.0% as determined by SDS-PAGE. |
| Description |
CST5 Human Recombinant produced in E. coli is a single polypeptide chain containing 123 amino acids (26-142) and having a molecular mass of 14.36kDa.CST5 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques. |
| Protein Background |
Cystatin 5 (CST5) is a novel member of the cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. Some members are active cysteine protease inhibitors, while others have lost or possibly never had this inhibitory activity. The superfamily is comprised of 3 inhibitory families: the type 1 cystatins (stefins), type 2 cystatins and the kininogens. Type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in various human fluids and secretions. |
| Expression host |
Escherichia Coli. |
| Synonyms |
Cystatin-D, CST5, Cystatin 5, Cystatin-5. |
| Reagent Appearance |
Sterile Filtered clear solution. |
| Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence |
QSRTLAGGIH ATDLNDKSVQ RALDFAISEY NKVINKDEYY SRPLQVMAAY QQIVGGVNYY FNVKFGRTTC TKSQPNLDNC PFNDQPKLKE EEFCSFQINE VPWEDKISIL NYKCRKVHHH HHH. |
| Biological Activity |
The IC50 value is |
