| Formulation |
CLEC5A protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer, (pH8.0) and 10% glycerol. |
| Purity |
Greater than 80.0% as determined by SDS-PAGE. |
| Description |
CLEC5A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids (28-188 a.a) and having a molecular mass of 20.8kDa.CLEC5A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background |
C-type lectin superfamily member 5 (CLECSF5) and myeloid DAP12-associating lectin 1 (MDL1), aka CLE5CA is a C-type lectin. CLE5CA is a member of a significant myeloid lineage activating pathway. The CLE5CA protein acts as a positive regulator of osteoclastogenesis and regulates inflammatory responses. |
| Expression host |
Escherichia Coli. |
| Synonyms |
C-type lectin domain family 5 member A , CLECSF5, MDL-1, MDL1, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1. |
| Reagent Appearance |
Sterile Filtered clear solution. |
| Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MGSPQIFNKS NDGFTTTRSY GTVSQIFGSS SPSPNGFITT RSYGTVCPKD WEFYQARCFF LSTSESSWNE SRDFCKGKGS TLAIVNTPEK LKFLQDITDA EKYFIGLIYH REEKRWRWIN NSVFNGNVTN QNQNFNCATI GLTKTFDAAS CDISYRRICE KNAK.. |
