BEX1 Human

Data sheet

Formulation

The BEX1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol.

Purity

Greater than 80% as determined by SDS-PAGE.

Description

BEX1 Human Recombinant produced in E. coli is a single polypeptide chain containing 148 amino acids (1-125) and having a molecular mass of 17.2kDa. BEX1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques

Protein Background

Brain Expressed X-Linked 1 (BEX1) which participates in cell cycle progression and neuronal differentiation, is a signaling adapter molecule involved in p75NTR/NGFR signaling. BEX1 inhibits neuronal differentiation in response to nerve growth factor. BEX1

Expression host

Escherichia Coli.

Synonyms

BEX2, HBEX2, HGR74-h, Protein BEX1, Brain-expressed X-linked protein 1.

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMESKEKR AVNSLSMENA NQENEEKEQV ANKGEPLALP LDAGEYCVPR GNRRRFRVRQ PILQYRWDMM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP.