APOBEC4 Human

Data sheet

Formulation

APOBEC4 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.

Purity

Greater than 85% as determined by SDS-PAGE.

Description

APOBEC4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 390 amino acids (1-367aa) and having a molecular mass of 44kDa.APOBEC4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chro

Protein Background

APOBEC4 belongs to the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Further AID/APOBEC family members are implicated in Mrna editing, somatic hypermutation and recombination of immunoglobulin genes, an

Expression host

Escherichia Coli.

Synonyms

Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 4 (Putative), C1orf169, Apolipoprotein B MRNA-Editing Enzyme Catalytic Polypeptide-Like 4, Chromosome 1 Open Reading Frame 169, Putative C->U-Editing Enzyme APOBEC-4, EC 3.5.4.

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTE FCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRH IILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSG SH