For research use only. Not for diagnostic or therapeutic use, or for human or veterinary use. Sold only to research institutions and qualified laboratory professionals. Not for sale to individuals for personal use.
Sm-D2, SMD2, snRNP core protein D2, SNRPD1, SNRPD2, Small nuclear ribonucleoprotein Sm D2
Data sheet
Formulation
SNRPD2 is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol.
Purity
Greater than 80% as determined by SDS-PAGE.
Applications
Western blot with anti-Sm positive patient sera.
Description
SNRPD2 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 14,773 Dalton. SNRPD2 is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
Protein Background
SNRPD2 is a member of the small nuclear ribonucleoprotein core protein family. SNRPD2 is a small nuclear ribonucleoprotein (snRNPs) which comprises the spliceosome in eukaryotes. SNRPD2 is required for pre-mRNA splicing and small nuclear ribonucleoprotein
Expression host
Sf9 insect cells.
Synonyms
Small nuclear ribonucleoprotein Sm D2, Sm-D2, snRNP core protein D2, SNRPD2, SNRPD1, SMD2.
Reagent Appearance
Sterile Filtered clear solution.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Immunological functions
1. Binds IgG-type human auto-antibodies.2. Standard ELISA test (checker-board analysis of positive/negative sera panels including CDC international reference sera).
Coating concentration
0.4-0.8 ug/ml (depending on the type of ELISA plate and coating buffer). Suitable for biotinylation and iodination.
Method
The sale and/or commercial use of Recombinant Human Transforming Growth Factor Beta Receptor II (TGFBR2) is prohibited in the United States of America (U.S.A).
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