NR-E11149
Human FGFR substrate 2 (FRS2) ELISA KitÂ
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The kit is used to quantify the human FRS2 in cell culture supernatant, serum, and other suitable sample solution. Does not show cross-reactivity related molecules.
Standard range 31.2 - 2000 pg/mL
Assay time 4 h 40 min
Validity 6 months
Store at 2-8 °C
Background:
Fibroblast growth factor receptor substrate 2 in humans is encoded by the FRS2 gene. The docking protein FRS2 is implicated in the transmission of extracellular signals from the fibroblast growth factor (FGF) or nerve growth factor (NGF) receptors to the Ras/mitogen activated protein kinase signaling cascade. FRS2 is overexpressed and amplified in several cancer types, including prostate cancer.
FOR RESEARCH USE ONLY