Human C4 Protein

Background:

Native human C4 is a naturally glycosylated (6.9%) polypeptide containing three disulfide-linked chains.  C4 plays a key role in the activation of both the classical and the lectin pathways of complement activation.

Storage:

-70 C or below. Avoid freeze/thaw.

Source:

Normal human serum

Activity:

 >80% versus normal human serum standard

Purity:

>90% by SDS-PAGE

Molecular Weight:

Size:

205,000 Da (3 chains)

250 µg/vial

Concentration:

1.0 mg/ml

Buffer:

10 mM sodium phosphate, 145 mM NaCl, pH 7.3

Preservative:

None, 0.22 µm filtered