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CD31-Biotinylated, Mouse Anti Human ( CD31 Biotin Antibody )
TypeMouse Anti Human Monoclonal.ClonehCD31ImmunogenEnriched human plateletsIg Subclassmouse IgG1Purification MethodProtein AProtein formulation1mg/ml in PBS (after reconstitution).Shipping ConditionsAntibody is shipped lyophilized at ambient
Data sheet
| Reconstitution | 1mg/ml in PBS (after reconstitution). |
| Clone | hCD31 |
| Applications | Flow cytometry, immunohistochemistry. For staining, use 10ul/106 cells. |
| Protein Background | CD31 is a glycoprotein expressed on endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts, neutrophils. In humans, the gene encoding CD31 is found on chromosome 17.CD31 is a cluster of differentiation molecule. It is also called PECAM-1 for platelet endothelial cell adhesion molecule. It plays a key role in removing aged neutrophils from the body. Both the neutrophil and the macrophage express CD31 on their membranes, and during the testing process, these CD31 molecules bind the two cells together. If the neutrophil is healthy, it will send a signal to the macrophage, and the CD31 molecules will detach. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas and carcinomas. |
| Synonyms | Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', CD31 antigen, PECAM1, CD31. |
| Type | Mouse Anti Human Monoclonal. |
| Immunogen | Enriched human platelets |
| Ig Subclass | mouse IgG1 |
| Purification Method | Protein A |
| Protein formulation | 1mg/ml in PBS (after reconstitution). |
| Storage Procedures | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
| Antibody Properties | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
| Available Conjugates | Blocking and staining antibody. For staining, use 10ul/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator. |
| Immunological function | This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10ul/106 cells. |