Mouse Neutrophil Elastase/ ELA2 ELISA Kit

The kit is used to quantify the mouse neutrophil elastase (ELA2) in cell culture supernatant serum, and other suitable sample solution. Exhibits no cross-reactivity with serpins A1a, A1c and SLP1.  

Standard range          12.5 - 800 pg/mL

Assay time                   4 h 40 min  

Validity                         Six months                                

Store at                        2-8 °C 

Background:

Aliases: leukocyte elastase, ELANE, ELA2, elastase 2, PMN elastase

Neutrophil Elastase (ELA2) is a serine protease and belongs to the chymotrypsin family. It is secreted mainly by the neutrophils and macrophages during inflammation and helps in the degradation of many extracellular matrix proteins. It is also involved in the degradation of proteins in azurophil granules (neutrophil lysosomes). ELA2 may be involved in lung emphysema, cystic fibrosis, the adult respiratory distress syndrome (ARDS), rheumatoid arthritis, tumor invasion and infectious diseases.

FOR RESEARCH USE ONLY