Human Calpain-1 Catalytic Subunit ( CAPN1 )

Catalog # PT_40081

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$344.00
DescriptionCAPN1 consists of an 80-kDa large subunit and a 30 kDa small subunit. CAPN1 was purified by sequential chromatography through DEAE-Sepharose, A1.5m Bio-Gel, and Phenyl-Sepharose CL-4B columns.SourceHuman Erythrocytes.Physical
Product Size: 2ug
Quantity

Data sheet

Formulation
50mM imidazole-HCl, 100mM NaCl, 5mM EGTA, 1mM DTT and 10% sucrose.
Purity
Greater than 90% as determined by SDS-PAGE.
Description
CAPN1 consists of an 80-kDa large subunit and a 30 kDa small subunit. CAPN1 was purified by sequential chromatography through DEAE-Sepharose, A1.5m Bio-Gel, and Phenyl-Sepharose CL-4B columns.
Protein Background
Calpains activity is attributed to two main isoforms: ?-calpain and m-calpain, which are ubiquitously, expressed proteases implicated in cellular migration, cell cycle progression, degenerative processes and cell death. These heterodimeric enzymes are com
Expression host
Human Erythrocytes.
Synonyms
Calpain-1 catalytic subunit, EC 3.4.22.52, Calpain-1 large subunit, Calcium-activated neutral proteinase 1, Calpain mu-type, muCANP, Micromolar-calpain, Cell proliferation-inducing gene 30 protein, CANP 1, CAPN1, CANPL1, PIG30, CANP, muCL, CANP1.
Reagent Appearance
Sterile Filtered colorless solution.
Stability
CAPN1 although stable at 10°C for 1 week, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
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