GRO-Alpha Human Recombinant ( CXCL1 ) ( GRO a Human )

Catalog # PT_40740

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$201.00
DescriptionGRO Alpha Human Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7811 Dalton. The GRO-alpha is purified by proprietary chromatographic
Product Size: 5ug
Quantity

Data sheet

Formulation
Lyophilized from a 0.2um filtered concentrated (1mg/ml) solution in 20mM PB, pH 7.4, 50mM NaCl.
Solubility
It is recommended to reconstitute the lyophilized CXCL1 in sterile 18M-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Purity
Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Description
GRO Alpha Human Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7811 Dalton. The GRO-alpha is purified by proprietary chromatographic techniques.
Protein Background
Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). It is secreted b
Expression host
Escherichia Coli.
Synonyms
Growth-regulated protein alpha, CXCL1, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO-alpha (1-73), chemokine (C-X-C motif) ligand 1, GRO1, GROa, SCYB1, MGSA-a, MGSA alpha.
Reagent Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Stability
Lyophilized GRO-alpha although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to a
Amino acid sequence
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Ser-Val-Ala-Thr.
Biological Activity
Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.
References
Title:Deficient inflammatory response to UV radiation in neonatal mice.Publication:Published online before print March 16, 2007, doi: 10.1189/jlb.1206729 June 2007 Journal of Leukocyte Biology vol. 81 no. 6 1352-1361 Link:http://www.jleukbio.org/content/8
Product Description
Immunoreactive with sera of HCV-infected individuals.
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