Interleukin-31 Mouse Recombinant ( IL31 Mouse )

Data sheet

Formulation

The IL31 (1mg/ml) was lyophilized from 10mM sodium Phosphate pH-7.4.

Solubility

It is recommended to reconstitute the lyophilized IL31 in sterile 18M?-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 97.0% as determined by(a) Analysis by SEC-HPLC.(b) Analysis by SDS-PAGE.

Description

IL31 mouse recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids and having a molecular mass of 15.7 kDa.

Protein Background

IL-31 produced by activated Th2-type T cells, cooperates with a heterodimeric receptor consisting of IL-31 Receptor Anatagonist and Onconstatin-M Receptor that is continuesly expressed on epithelial cells and keratinocytes. IL-31 plays a role in the promo

Expression host

Escherichia Coli.

Synonyms

Interleukin 31, IL31, IL-31.

Stability

Lyophilized IL31 Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL31 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

Amino acid sequence

MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C.

Physical Appearence

Sterile Filtered White lyophilized (freeze-dried) powder.