Interleukin-12 p40 Human Recombinant, Plant ( IL 12 p40 Human, Plant )

Data sheet

Formulation

Lyophilized from 1mg/ml solution in 20 mM PBS buffer pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized IL-12 p40 in sterile 18M?-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 97.0% as determined by Analysis by SDS-PAGE.

Description

IL-12 p40 human Recombinant produced in Nicotiana benthamiana plant is a glycosilated polypeptide chain containing 312 amino acids, 23-328 aa (molecular formula C1575H2420N424O490S12).IL-12 p40 is fused to a 6-His-tag at the N-terminal having the total mo

Protein Background

Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating

Expression host

Nicotiana benthamiana plant

Synonyms

NKSF2, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), TSF, Edodekin-alpha, IL-12 p40, IL-12B, IL-12 subunit p40, NK cell stimulatory factor chain 2.

Reagent Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Stability

Lyophilized IL-12 p40 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-12 p40 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended

Amino acid sequence

HHHHHHIWEL KKDVYVVELD WYPDAPGEMV VLTCDTPEED GITWTLDQSS EVLGSGKTLT IQVKEFGDAG QYTCHKGGEV LSHSLLLLHK KEDGIWSTDI LKDQKEPKNK TFLRCEAKNY SGRFTCWWLT TISTDLTFSV KSSRGSSDPQ GVTCGAATLS AERVRGDNKE YEYSVECQED SACPAAEESL PIEVMVDAVH KLKYENYTSS FFIRDIIKPD PPKNLQLKPL KN

Titer

Antibody is shipped in liquid form with ice packs.

Mouse Isotype

PBS pH 7.0, 0.005% Sodium Azide & 50% glycerol.