Interleukin-28A Human Recombinant, HEK ( IL 28A Human, HEK )

Data sheet

Formulation

The IL28A was lyophilized from 1mg/ml in 1xPBS.

Solubility

It is recommended to reconstitute the lyophilized IL-28A in sterile water not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 95% as obsereved by SDS-PAGE.

Description

Interleukin-28A Human Recombinant produced in HEK cells is a non-glycosylated monomer, having a total molecular weight of 24kDa.The IL28A is purified by proprietary chromatographic techniques.

Protein Background

IL-28A is distantly related to type I interferons and the IL-10 family. Expression of IL-28A is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleu

Expression host

HEK.

Synonyms

Interleukin-28A, IL-28A, IFN-Lambda 2, Interferon-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20.

Stability

Lyophilized IL-28A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL28A should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a

Physical Appearence

Sterile Filtered White lyophilized (freeze-dried) powder.

Biological Activity

The specific activity was determined by the dose dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus and is typically 0.5-5ng/ml.