TIMP2 Antibody View larger

TIMP2 Antibody

ASA-B1863

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

TIMP metallopeptidase inhibitor 2PolyclonalIgGRabbitHuman, Mouse, RatELISA, IHC-PImmunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP2(205-220aa RGAAPPKQEFLDIEDP), identical to the related mouse and rat sequences.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

TIMP2

Protein

Metalloproteinase inhibitor 2

Uniprot ID

P16035

Function

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

Tissue Specificity

 

Sub-cellular localization

Secreted.

Sequence Similarities

Belongs to the protease inhibitor I35 (TIMP) family.

Aliases

CSC 21K antibody|CSC-21K antibody|CSC21K antibody|Metalloproteinase inhibitor 2 antibody|Metalloproteinase inhibitor 2 precursor antibody|TIMP 2 antibody|TIMP metallopeptidase inhibitor 2 antibody|TIMP-2 antibody|TIMP2 antibody|TIMP2_HUMAN antibody|Tissue Inhibitor of Metalloproteinase 2 antibody|Tissue inhibitor of metalloproteinases 2 antibody

Application Details

ApplicationConcentration*SpeciesValidated Using**
Immunohistochemistry(Paraffin-embedded Section)0.5-1μg/mlHuman Mouse, RatAssaySolutio's IHC/ICC Detection kit
ELISA0.1-0.5μg/mlHuman Mouse, RatSandwich ELISA format


AssaySolution recommends Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information

Anti-TIMP2 antibody, ASA-B1863, IHC(P)
IHC(P): Human Mammary Cancer Tissue
 
 
 
 
 

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