More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| colony stimulating factor 1 (macrophage) | Polyclonal | IgG | Rabbit | Mouse, Rat | ELISA, IHC-P | Immunogen affinity purified. |
Immunogen | ||||||
| E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | CSF1 |
Protein | Macrophage colony-stimulating factor 1 |
Uniprot ID | P07141 |
Function | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. |
Tissue Specificity | |
Sub-cellular localization | Cell membrane ; Single-pass type I membrane protein . |
Sequence Similarities | |
Aliases | Colony stimulating factor 1 (macrophage) antibody|Colony stimulating factor 1 antibody|Colony stimulating factor macrophage specific antibody|CSF 1 antibody| CSF-1 antibody|CSF1 antibody|CSF1_HUMAN antibody|Csfm antibody| Lanimostim antibody|M CSF antibody|M-CSF antibody|Macrophage Colony Stimulating Factor 1 antibody|Macrophage colony stimulating factor antibody| MCSF antibody|MGC31930 antibody|Processed macrophage colony-stimulating factor 1 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Mouse, Rat | AssaySolutio's IHC/ICC Detection kit |
| ELISA | 0.1-0.5μg/ml | Mouse | Sandwich ELISA format |
AssaySolution recommends Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti- MCSF antibody, ASA-B1245, IHC(P)
IHC(P): Mouse Spleen Tissue
IHC(P): Mouse Spleen Tissue
Anti- MCSF antibody, ASA-B1245, IHC(P)
IHC(P): Rat Spleen Tissue
IHC(P): Rat Spleen Tissue
