More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| glucagon | Monoclonal | IgG | Mouse | Human, Mouse, Rabbit, Rat | IHC-P | Ascites |
Immunogen |
| Polymerized porcine glucagon. |
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Mouse ascites fluid, 1.2% sodium acetate, 2 mg BSA, with 0.01 mg NaN3 as preservative. *carrier free antibody available upon request. |
Concentration | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100 µg/ml. |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | GCG |
Protein | Glucagon |
Uniprot ID | Human(P01275), Mouse(P55095), Rat(P06883) |
Function | Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. |
Tissue Specificity | Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain. |
Sub-cellular localization | Secreted. |
Sequence Similarities | Belongs to the glucagon family. |
Aliases | GLP1|GLP2|glicentin-related polypeptide|glucagon-like peptide 1|glucagon-like peptide 2 |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Immunohistochemistry(Paraffin-embedded Section) | 1-2μg/ml | Human, mouse, rat, rabbit | AssaySolutio's IHC/ICC Detection kit |
AssaySolution recommends Mouse Peroxidase IHC/ICC Detection Kit (AKIT004B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-Glucagon antibody (monoclonal), ASA-B0791, IHC(P)
IHC(P): Rat Pancreas Tissue
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