More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| plasminogen activator, urokinase receptor | Polyclonal | IgG | Rabbit | Human | IHC-P, WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the C-terminus of human uPA Receptor(293-304aa CNHPDLDVQYRS). | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | PLAUR |
Protein | Urokinase plasminogen activator surface receptor(U-PAR/uPAR) |
Uniprot ID | Q03405 |
Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
Tissue Specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
Sub-cellular localization | Cell membrane. |
Sequence Similarities | Contains 3 UPAR/Ly6 domains. |
Aliases | CD 87 antibody|CD87 antibody|CD87 antigen antibody|MO 3 antibody|MO3 antibody|Monocyte activation antigen Mo3 antibody|Plasminogen activator urokinase receptor antibody|PLAUR antibody|U PAR antibody|u plasminogen activator receptor antibody|U-PAR antibody|UPA receptor antibody|UPAR antibody|UPAR_HUMAN antibody|Urinary plasminogen activator receptor antibody|URKR antibody|Urokinase plasminogen activator receptor antibody|Urokinase plasminogen activator surface receptor antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human | AssaySolutio's ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human | AssaySolutio's IHC/ICC Detection kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-uPA Receptor antibody, ASA-B1954, Western blotting
Lane 1: MCF-7 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: RAJI Cell Lysate
Lane 4: SMMC Cell Lysate
Lane 1: MCF-7 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: RAJI Cell Lysate
Lane 4: SMMC Cell Lysate
Anti-uPA Receptor antibody, ASA-B1954, IHC(P)
IHC(P): Human Mammary Cancer Tissue
IHC(P): Human Mammary Cancer Tissue
