SNAP25 Antibody View larger

SNAP25 Antibody

ASA-B1740

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

synaptosomal-associated protein, 25kDa Polyclonal IgG Rabbit Human, Mouse, Rat IHC-P, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human SNAP25(186-200aa DSNKTRIDEANQRAT), identical to the related rat and mouse sequences.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

SNAP25

Protein

Synaptosomal-associated protein 25(SNAP-25)

Uniprot ID

P60880

Function

t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

Tissue Specificity

Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.

Sub-cellular localization

Cytoplasm, perinuclear region . Cell membrane.

Sequence Similarities

Belongs to the SNAP-25 family.

Aliases

bA416N4.2 antibody|Bdr antibody|dJ1068F16.2 antibody|FLJ23079 antibody|HGNC:11132 antibody|MGC105414 antibody|MGC139754 antibody|Resistance to inhibitors of cholinesterase 4 homolog antibody|RIC 4 antibody|RIC4 antibody|SEC 9 antibody|SEC9 antibody|SNAP 25 antibody|SNAP antibody|SNAP-25 antibody|SNAP-25B antibody|SNAP25 antibody|SNP 25 antibody|SNP25 antibody|SNP25_HUMAN antibody|sp antibody|SUP antibody|Super protein antibody|Synaptosomal associated 25 kDa protein antibody|Synaptosomal associated protein antibody|Synaptosomal Associated Protein 25 antibody|Synaptosomal associated protein 25kDa antibody|Synaptosomal-associated 25 kDa protein antibody|Synaptosomal-associated protein 25 antibody|Synaptosomal-associated protein, 25-KD antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Rat Human, MouseAssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml Rat Human, MouseAssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-SNAP25 antibody, ASA-B1740, Western blotting
WB: Rat Brain Tissue Lysate
Anti-SNAP25 antibody, ASA-B1740, IHC(P)
IHC(P): Rat Brain Tissue

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