Protein C Antibody

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
protein C(inactivator of coagulation factors Va and VIIIa)	Polyclonal	IgG	Rabbit	Human	IHC-P, WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Protein C(446-461aa HGHIRDKEAPQKSWAP).

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	PROC
Protein	Vitamin K-dependent protein C
Uniprot ID	P04070
Function	Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.
Tissue Specificity	Plasma; synthesized in the liver.
Sub-cellular localization	Secreted.
Sequence Similarities	Belongs to the peptidase S1 family.
Aliases	Activation peptide antibody|Anticoagulant protein C antibody|APC antibody|Autoprothrombin IIA antibody|Blood coagulation factor XIV antibody|EC 3.4.21.69 antibody|PC antibody|proC antibody|PROC_HUMAN antibody|PROC1 antibody|Protein C(inactivator of coagulation factors Va and VIIIa) antibody|THPH3 antibody|THPH4 antibody|Vitamin K dependent protein C antibody|Vitamin K dependent protein C precursor antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human	AssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	0.5-1μg/ml	Human	AssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information