Proprotein Convertase 2 Antibody View larger

Proprotein Convertase 2 Antibody

ASA-B1580

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

proprotein convertase subtilisin/kexin type 2 Polyclonal IgG Rabbit Human, Mouse, Rat IHC-P, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Proprotein Convertase 2(110-125aa GYRDINEIDINMNDPL), identical to the related mouse and rat sequences.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

PCSK2

Protein

Neuroendocrine convertase 2

Uniprot ID

P16519

Function

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.

Tissue Specificity

Sub-cellular localization

Cytoplasmic vesicle, secretory vesicle. Note: Localized in the secretion granules.

Sequence Similarities

Belongs to the peptidase S8 family. Furin subfamily.

Aliases

KEX2 like endoprotease 2 antibody|KEX2-like endoprotease 2 antibody|NEC 2 antibody|NEC2 antibody|NEC2_HUMAN antibody|Neuroendocrine convertase 2 antibody|PC2 antibody|PCSK2 antibody|Prohormone convertase 2 antibody|Proprotein convertase 2 antibody|Proprotein convertase subtilisin/kexin type 2 antibody|SPC2 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human Mouse, RatAssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml Human, Rat MouseAssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-Proprotein Convertase 2 antibody, ASA-B1580, IHC(P)
IHC(P): Rat Pancreas Tissue
Anti-Proprotein Convertase 2 antibody, ASA-B1580, Western blotting
All lanes: Anti Proprotein Convertase 2 (ASA-B1580) at 0.5ug/ml
WB: PANC Whole Cell Lysate at 40ug
Predicted bind size: 71KD
Observed bind size: 71KD

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