More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| mucin 5AC, oligomeric mucus/gel-forming | Monoclonal | IgG | Mouse | Human, Mouse, Rabbit, Rat | IHC-P, ICC, WB | Ascites |
Immunogen |
| Mucin from human ovarian cyst fluid. |
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Mouse ascites fluid, 1.2% sodium acetate, 2 mg BSA, with 0.01 mg NaN3 as preservative. *carrier free antibody available upon request. |
Concentration | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100 µg/ml. |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | MUC5AC |
Protein | Mucin-5AC |
Uniprot ID | Human(P98088) |
Function | Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. |
Tissue Specificity | Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum. |
Sub-cellular localization | Secreted. |
Sequence Similarities | Contains 1 CTCK (C-terminal cystine knot-like) domain. |
Aliases | Apomucin|Gastric mucin|LeB|Lewis B blood group antigen|Major Airway Glycoprotein|MUC 5|MUC5|MUC5AC|Mucin 5 subtype AC tracheobronchial|Mucin 5 Subtypes A And C|Mucin 5 subtypes A and C tracheobronchial/gastric|Mucin 5AC|Mucin 5AC oligomeric mucus/gel forming|Mucin 5AC, oligomeric mucus/gel forming pseudogene|TBM|Tracheobronchial Mucin |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 1-2μg/ml | Human, mouse, rabbit, rat | AssaySolutio's ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 2-4μg/ml | Human, mouse, rabbit, rat | AssaySolutio's IHC/ICC Detection kit |
| Immunocytochemistry | Suitable | Human, mouse, rabbit, rat | AssaySolutio's IHC/ICC Detection kit |
AssaySolution recommends Mouse Chemiluminescent WB Detection Kit (AKIT003B) for Western blot, and Mouse Peroxidase IHC/ICC Detection Kit (AKIT004B) for IHC(P) and ICC. *Blocking peptide can be purchased at $65. Contact us for more information
Anti- Mucin Gastric antibody, ASA-B1329, IHC(P)
IHC(P): Human Gastric Cancer Tissue
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