More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| ATP-binding cassette, sub-family C(CFTR/MRP), member 1 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | IHC-P, WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the C-terminus of human MRP1(1514-1531aa, LLQQRGLFYSMAKDAGLV), different from the related rat and mouse sequences by one amino acid. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | ABCC1 |
Protein | Multidrug resistance-associated protein 1 |
Uniprot ID | P33527 |
Function | Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. |
Tissue Specificity | Lung, testis and peripheral blood mononuclear cells. |
Sub-cellular localization | Cell membrane. |
Sequence Similarities | Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. |
Aliases | ABC 29 antibody|ABC29 antibody|ABCC 1 antibody|ABCC antibody|ABCC1 antibody|ATP binding cassette sub family C(CFTR/MRP) member 1 antibody|ATP binding cassette sub-family C member 1 antibody|ATP-binding cassette sub-family C member 1 antibody|DKFZp686N04233 antibody|DKFZp781G125 antibody|GS X antibody|GSX antibody|Leukotriene C(4) transporter antibody|LTC4 transporter antibody|MRP 1 antibody|MRP antibody|MRP1_HUMAN antibody|Multidrug resistance associated protein 1 antibody|Multidrug resistance protein antibody|Multidrug resistance-associated protein 1 antibody|Multiple drug resistance associated protein antibody|Multiple drug resistance protein 1 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human, Rat Mouse | AssaySolutio's ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human Mouse, Rat | AssaySolutio's IHC/ICC Detection kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-MRP1 antibody, ASA-B1310, Western blotting
Lane 1: JURKAT Cell Lysate
Lane 2: CEM Cell Lysate
Lane 3: A549 Cell Lysate
Lane 1: JURKAT Cell Lysate
Lane 2: CEM Cell Lysate
Lane 3: A549 Cell Lysate
Anti-MRP1 antibody, ASA-B1310, IHC(P)
IHC(P): Human Lung Cancer Tissue
IHC(P): Human Lung Cancer Tissue
