MRP1 Antibody

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
ATP-binding cassette, sub-family C(CFTR/MRP), member 1	Polyclonal	IgG	Rabbit	Human, Mouse, Rat	IHC-P, WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human MRP1(1514-1531aa, LLQQRGLFYSMAKDAGLV), different from the related rat and mouse sequences by one amino acid.

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	ABCC1
Protein	Multidrug resistance-associated protein 1
Uniprot ID	P33527
Function	Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Tissue Specificity	Lung, testis and peripheral blood mononuclear cells.
Sub-cellular localization	Cell membrane.
Sequence Similarities	Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Aliases	ABC 29 antibody|ABC29 antibody|ABCC 1 antibody|ABCC antibody|ABCC1 antibody|ATP binding cassette sub family C(CFTR/MRP) member 1 antibody|ATP binding cassette sub-family C member 1 antibody|ATP-binding cassette sub-family C member 1 antibody|DKFZp686N04233 antibody|DKFZp781G125 antibody|GS X antibody|GSX antibody|Leukotriene C(4) transporter antibody|LTC4 transporter antibody|MRP 1 antibody|MRP antibody|MRP1_HUMAN antibody|Multidrug resistance associated protein 1 antibody|Multidrug resistance protein antibody|Multidrug resistance-associated protein 1 antibody|Multiple drug resistance associated protein antibody|Multiple drug resistance protein 1 antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human, Rat Mouse	AssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	0.5-1μg/ml	Human Mouse, Rat	AssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information