ITPR3 Antibody

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
inositol 1,4,5-trisphosphate receptor, type 3	Polyclonal	IgG	Rabbit	Human, Mouse, Rat	IHC-P, WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human ITPR3 (70-95aa QYWKAKQTKQDKEKIADVVLLQKLQH), identical to the related mouse and rat sequences.

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	ITPR3
Protein	Inositol 1,4,5-trisphosphate receptor type 3
Uniprot ID	Q14573
Function	Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
Tissue Specificity	Expressed in intestinal crypt and villus epithelial cells.
Sub-cellular localization	Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence Similarities	Belongs to the InsP3 receptor family.
Aliases	4 antibody|5-trisphosphate receptor antibody|5-trisphosphate receptor type 3 antibody| FLJ36205 antibody|Inositol 1 antibody|Inositol 1,4,5 trisphosphate receptor type 3 antibody|InsP3R3 antibody|IP3 receptor antibody|IP3 receptor isoform 3 antibody|IP3R 3 antibody|IP3R antibody|IP3R3 antibody|ITPR 3 antibody|ITPR3 antibody|ITPR3_HUMAN antibody| Type 3 inositol 1 antibody|Type 3 inositol 1,4,5 trisphosphate receptor antibody|Type 3 InsP3 receptor antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human	AssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	0.5-1μg/ml	Human, Mouse, Rat	AssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information