More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor) | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | IHC-P, WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin alpha 3(1026-1040aa ALYEAKRQKAEMKSQ), identical to the related mouse and rat sequences. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | ITGA3 |
Protein | Integrin alpha-3 |
Uniprot ID | P26006 |
Function | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
Tissue Specificity | Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells. |
Sub-cellular localization | Cell membrane. |
Sequence Similarities | Belongs to the integrin alpha chain family. |
Aliases | AA407068 antibody|Antigen identified by monoclonal antibody J143 antibody|CD49 antigen like family member C antibody|CD49 antigen-like family member C antibody|CD49c antibody|CD49c antigen antibody|FLJ34631 antibody|FLJ34704 antibody|FRP 2 antibody|FRP-2 antibody|FRP2 antibody|galactoprotein B3 antibody|GAP B3 antibody|GAPB3 antibody|Integrin alpha 3 antibody|Integrin alpha-3 light chain antibody|Integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody|ITA3_HUMAN antibody|ITGA 3 antibody|ITGA3 antibody|MSK18 antibody|URO1 antibody|VCA 2 antibody|VCA2 antibody|Very late activation protein 3 receptor alpha 3 subunit antibody|Very Late Activation Protein 3 Receptor Alpha 3 Subunit antibody|VL3A antibody|VLA 3 alpha chain antibody|VLA 3 subunit alpha antibody|VLA-3 subunit alpha antibody|VLA3 antibody|VLA3a antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Rat Human, Mouse | AssaySolutio's ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human Mouse, Rat | AssaySolutio's IHC/ICC Detection kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-Integrin alpha 3 antibody, ASA-B1041, Western blotting
WB: Rat Liver Tissue Lysate
WB: Rat Liver Tissue Lysate
Anti-Integrin alpha 3 antibody, ASA-B1041, IHC(P)
IHC(P): Human Intestinal Cancer Tissue
IHC(P): Human Intestinal Cancer Tissue
