ASA-B0547
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CYP24A1 Antibody
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Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
cytochrome P450, family 24, subfamily A, polypeptide 1 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | IHC-P, WB | Immunogen affinity purified. |
Immunogen | ||||||
E.coli-derived human CYP24A1 recombinant protein (Position: E153-R514). Human CYP24A1 shares 86.2% amino acid (aa) sequence identity with both mouse and rat CYP24A1. |
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Gene | CYP24A1 |
Protein | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial |
Uniprot ID | Q07973 |
Function | Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product. |
Tissue Specificity | |
Sub-cellular localization | Mitochondrion. |
Sequence Similarities | |
Aliases | 1 25 @dihydroxyvitamin D3 24 hydroxylase antibody|1 25 dihydroxyvitamin D(3) 24 hydroxylase antibody|1 antibody|1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial antibody|24 ohase antibody|24-OHase antibody|25-dihydroxyvitamin D(3) 24-hydroxylase antibody|CP 24 antibody|CP24 antibody| CP24A_HUMAN antibody|CYP 24 antibody|CYP24 antibody|CYP24A1 antibody| Cytochrome P450 24A1 antibody| Cytochrome P450 24A1 mitochondrial antibody|cytochrome P450 CC24 antibody|Cytochrome P450 family 24 antibody|Cytochrome P450 family 24 subfamily A polypeptide 1 antibody| Cytochrome P450 subfamily XXIV antibody|Cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) antibody|Cytochrome P450-CC24 antibody|EC 1.14.13.n4 antibody|Exo mitochondrial protein antibody|HCAI antibody| MGC126273 antibody| MGC126274 antibody|mitochondrial antibody|P450 CC24 antibody|Vitamin D 24 hydroxylase antibody|Vitamin D(3) 24 hydroxylase antibody| Vitamin D(3) 24-hydroxylase antibody |
Application | Concentration* | Species | Validated Using** |
Western blot | 0.1-0.5μg/ml | Human, Mouse, Rat | AssaySolutio's ECL kit |
Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human, Mouse, Rat | AssaySolutio's IHC/ICC Detection kit |