More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| chemokine (C-X-C motif) receptor 3 | Polyclonal | IgG | Rabbit | Human, Rat | IHC-P, WB | Immunogen affinity purified. |
Immunogen | ||||||
| E.coli-derived human CXCR3 recombinant protein (Position: M1-L368). Human CXCR3 shares 86% amino acid (aa) sequence identity with both mouse and rat CXCR3. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | CXCR3 |
Protein | C-X-C chemokine receptor type 3 |
Uniprot ID | P49682 |
Function | Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response. |
Tissue Specificity | Isoform 1 and isoform 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta. Isoform 2 is expressed in endothelial cells. Expressed in T-cells (at protein level). |
Sub-cellular localization | Isoform 1: Cell membrane. |
Sequence Similarities | Belongs to the G-protein coupled receptor 1 family. |
Aliases | C-X-C chemokine receptor type 3 antibody|CD 183 antibody|CD182 antibody|CD183 antibody|Chemokine (C X C motif) receptor 3 antibody|Chemokine (C X C) receptor 3 antibody|Chemokine CXC Motif Receptor 3 antibody|CKR L2 antibody|CKR-L2 antibody|CKRL2 antibody|CMKAR3 antibody|CXC-R3 antibody|CXCR-3 antibody|CXCR3 antibody|CXCR3_HUMAN antibody|G Protein Coupled Receptor 9 antibody|G protein-coupled receptor 9 antibody|GPR9 antibody|Interferon-inducible protein 10 receptor antibody|IP-10 receptor antibody|IP10 antibody|IP10 R antibody|IP10 receptor antibody|IP10-R antibody|IP10R antibody|Mig R antibody|Mig receptor antibody|Mig-R antibody|MIGR antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human | AssaySolutio's ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human, Rat | AssaySolutio's IHC/ICC Detection kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-CXCR3 antibody, ASA-B0522--1.jpg
IHC(P): Rat Kidney Tissue
IHC(P): Rat Kidney Tissue
Anti-CXCR3 antibody, ASA-B0522--2.jpg
IHC(P): Human Tonsil Tissue
IHC(P): Human Tonsil Tissue
Anti-CXCR3 antibody, ASA-B0522--3.jpg
IHC(P): Human Lung Cancer Tissue
IHC(P): Human Lung Cancer Tissue