CXCR1 Antibody View larger

CXCR1 Antibody

ASA-B0520

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

chemokine(C-X-C motif) receptor 1 Polyclonal IgG Rabbit Human IHC-P, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1(24-38aa DEDYSPCMLETETLN).

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

CXCR1

Protein

C-X-C chemokine receptor type 1

Uniprot ID

P25024

Function

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Tissue Specificity

Sub-cellular localization

Cell membrane; Multi-pass membrane protein.

Sequence Similarities

Belongs to the G-protein coupled receptor 1 family.

Aliases

C C antibody|C C CKR 1 antibody|C-X-C chemokine receptor type 1 antibody|CCCKR1 antibody|CD 181 antibody|CD128 antibody|CD181 antibody|CD181 antigen antibody|CDw128a antibody|Chemokine(C X C motif) receptor 1 antibody|Chemokine(C X C) receptor 1 antibody|Chemokine receptor 1 antibody|CKR 1 antibody|CMKAR1 antibody|CXC-R1 antibody|CXCR 1 antibody|CXCR-1 antibody|CXCR1 antibody|CXCR1_HUMAN antibody|High affinity interleukin 8 receptor A antibody|High affinity interleukin-8 receptor A antibody|IL 8 receptor type 1 antibody|IL 8R A antibody|IL-8 receptor type 1 antibody|IL-8R A antibody|IL8 receptor antibody|IL8 receptor type 1 antibody|IL8R1 antibody|IL8RA antibody|IL8RBA antibody|Interleukin 8 receptor alpha antibody|Interleukin 8 receptor type 1 antibody|Interleukin 8 receptor type A antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml HumanAssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml HumanAssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-CXCR1 antibody, ASA-B0520, Western blotting
All lanes: Anti CXCR1 (ASA-B0520) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: COLO320 Whole Cell Lysate at 40ug
Lane 3: M231 Whole Cell Lysate at 40ug
Lane 4: HT1080 Whole Cell Lysate at 40ug
Predicted bind size: 40KD
Observed bind size: 40KD
Anti-CXCR1 antibody, ASA-B0520, IHC(P)
IHC(P): Human Lung Cancer Tissue

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