CD95 Antibody View larger

CD95 Antibody

ASA-B0413

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

Fas(TNF receptor superfamily, member 6) Polyclonal IgG Rabbit Mouse, Rat IHC-P, IHC-F, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of rat CD95(87-109aa, YTDRKHYSDKCRRCAFCDEGHGL).

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

FAS

Protein

Tumor necrosis factor receptor superfamily member 6

Uniprot ID

Q63199

Function

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).

Tissue Specificity

Sub-cellular localization

Membrane; Single-pass type I membrane protein.

Sequence Similarities

Contains 1 death domain.

Aliases

ALPS 1A antibody|ALPS1A antibody|APO 1 antibody|Apo 1 antigen antibody|APO 1 cell surface antigen antibody|Apo-1 antigen antibody|APO1 antibody|Apo1 antigen antibody|APO1 cell surface antigen antibody|Apoptosis antigen 1 antibody|Apoptosis mediating surface antigen FAS antibody|Apoptosis-mediating surface antigen FAS antibody|APT 1 antibody|APT1 antibody|CD 95 antibody|CD 95 antigen antibody|CD95 antibody|CD95 antigen antibody|Delta Fas antibody|Delta Fas/APO 1/CD95 antibody|Delta Fas/APO1/CD95 antibody|Fas(TNF receptor superfamily, member 6) antibody|FAS 1 antibody|FAS 827dupA antibody|Fas AMA antibody|FAS antibody|FAS Antigen antibody|Fas cell surface death receptor antibody|FAS1 antibody|FASLG receptor antibody|FASTM antibody|sFAS antibody|Surface antigen APO1 antibody|TNF receptor superfamily, member 6 antibody|TNFRSF 6 antibody|TNFRSF6 antibody|TNR6_HUMAN antibody|Tumor necrosis factor receptor superfamily member 6 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Mouse, Rat AssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml Mouse, Rat AssaySolutio's IHC/ICC Detection kit
Immunohistochemistry(Frozen Section) 0.5-1μg/ml Mouse, Rat AssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P) and IHC(F). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-CD95 antibody, ASA-B0413, Western blotting
Lane 1: Recombinant Mouse FAS Protein 10ng
Lane 2: Recombinant Mouse FAS Protein 5ng
Lane 3: Recombinant Mouse FAS Protein 2.5ng
Anti-CD95 antibody, ASA-B0413, IHC(P)
IHC(P): Rat Spleen Tissue Lysate

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