CD244 Antibody

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
CD244 molecule, natural killer cell receptor 2B4	Polyclonal	IgG	Rabbit	Human	IHC-P, WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human CD244(357-370aa RLSRKELENFDVYS).

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	CD244
Protein	Natural killer cell receptor 2B4
Uniprot ID	Q9BZW8
Function	Modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
Tissue Specificity	Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils.
Sub-cellular localization	Membrane ; Single-pass type I membrane protein .
Sequence Similarities
Aliases	2B4 antibody|C9.1 antibody|CD244 antibody|CD244 antigen antibody|CD244 molecule natural killer cell receptor 2B4 antibody|CD244 natural killer cell receptor 2B4 antibody|CD244_HUMAN antibody|F730046O15Rik antibody|h2B4 antibody|Ly90 antibody|NAIL antibody|Natural killer cell activation-inducing ligand antibody|Natural killer cell receptor 2B4 antibody|NK cell activation inducing ligand antibody|NK cell activation inducing ligand NAIL antibody|NK cell activation-inducing ligand antibody|NK cell type I receptor protein 2B4 antibody|NKR2B4 antibody|Nmrk antibody|Non-MHC restricted killing associated antibody|OTTHUMP00000027884 antibody|p38 antibody|SLAM family, member 4 antibody|SLAMF4 antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human	AssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	0.5-1μg/ml	Human	AssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information