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Caspase-6(P18) Antibody View larger

Caspase-6(P18) Antibody

ASA-B0298

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 
caspase 6, apoptosis-related cysteine peptidase Polyclonal IgG Rabbit Mouse, Rat IHC-P, IHC-F, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of rat Caspase-6(P18)(7-27aa FYRSREVLDPAEQYKMDHKRR), different from the related mouse sequence by two amino acids.

Properties

Form

 Lyophilized

Size

 100 µg/vial

Contents

 Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

 Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

 At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

 CASP6

Protein

 Caspase-6

Uniprot ID

 O35397

Function

 Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity).

Tissue Specificity

Sub-cellular localization

 Cytoplasm .

Sequence Similarities

Aliases

 Apoptosis Related Cysteine Protease antibody|Apoptotic cysteine protease MCH2 antibody|Apoptotic protease MCH 2 antibody|Apoptotic protease Mch-2 antibody|Apoptotic protease MCH2 antibody|Casp 6 antibody|CASP-6 antibody|Casp6 antibody|Caspase 6 antibody|Caspase 6 apoptosis related cysteine protease antibody|Caspase 6 precursor antibody|Caspase 6, apoptosis related cysteine peptidase antibody|Caspase-6 subunit p18 antibody|Caspase6 antibody|Human cysteine protease Mch2 isoform alpha antibody|Mch 2 antibody|Mch2 antibody|OTTHUMP00000162742 antibody|OTTHUMP00000162743 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Mouse, RatAssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml Mouse, RatAssaySolutio's IHC/ICC Detection kit
Immunohistochemistry(Frozen Section) 0.5-1μg/ml Rat MouseAssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P) and IHC(F). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-Caspase-6(P18) antibody, ASA-B0298, Western blotting
Lane 1: Rat Liver Tissue Lysate
Lane 2: Rat Kidney Tissue Lysate
Lane 3: Rat Testis Tissue Lysate
Lane 4: NRK Cell Lysate
Lane 5: Mouse Liver Tissue Lysate
Lane 6: Mouse Kidney Tissue Lysate
Lane 7: Mouse Testis Tissue Lysate
Anti-Caspase-6(P18) antibody, ASA-B0298, IHC(P)
IHC(P): Rat Spleen Tissue
Anti-Caspase-6(P18) antibody, ASA-B0298, IHC(P)
IHC(P): Rat Intestine Tissue

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